Chromosome-scale assembly of the Cupressus sempervirens genome unravels new insights into the evolutionary history of conifers

How do conifers maintain some of the largest genomes in the plant kingdom?

Added on : 28 July 2026

We are proud to share our latest publication on BioRxiv, the result of a collaborative effort involving the CNRGV and our partners. Together, we present a chromosome-scale reference genome of Cupressus sempervirens, generated using PacBio HiFi sequencing and scaffolded with optical and genetic maps, delivering one of the most contiguous conifer genomes assembled to date. 🧬

TE dynamic evolution and paleogenomic reconstruction analysis reveal that the giant cypress genome has been shaped by the long-term accumulation of ancient transposable elements, rather than by recent bursts of activity or whole genome duplication. This new reference genome provides a valuable resource for studying conifer genome evolution, gene structure, and traits of ecological and agronomic importance, including cypress pollinosis.

This publication reflects the CNRGV's long-standing expertise in genome assembly and highlights our contribution to decoding some of the largest and most complex plant genomes such as conifers. 🤝

Congratulations to all the team and especially William Marande and Charlotte Cravero for their involvement and thank you to all our collaborators who contributed to this paper! 🎉

🔗 https://doi.org/10.64898/2026.07.23.736688