The wheat Sr50 gene reveals rich diversity at a cereal disease resistance locus
Nature Plants. Article number:15186 (2015). DOI:10.1038/nplants.2015.186
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Nature Plants. Article number:15186 (2015). DOI:10.1038/nplants.2015.186
Authors :
Rohit Mago, Peng Zhang, Sonia Vautrin, Hana Šimková, Urmil Bansal, Ming-Cheng Luo, Matthew Rouse, Haydar Karaoglu, Sambasivam Periyannan, James Kolmer, Yue Jin, Michael A. Ayliffe, Harbans Bariana, Robert F. Park, Robert McIntosh, Jaroslav Doležel, Hélène Bergès, Wolfgang Spielmeyer, Evans S. Lagudah, Jeff G. Ellis, Peter N. Dodds
Abstract :
We identify the wheat stem rust resistance gene Sr50 (using physical mapping, mutation and complementation) as homologous to barley Mla, encoding a coiled-coil nucleotide-binding leucine-rich repeat (CC-NB-LRR) protein. We show that Sr50 confers a unique resistance specificity different from Sr31 and other genes on rye chromosome 1RS, and is effective against the broadly virulent Ug99 race lineage. Extensive haplotype diversity at the rye Sr50 locus holds promise for mining effective resistance genes.